As IT and Operational Technology environments continue to converge, CISOs face a growing challenge: protecting systems that keep the business running while enabling innovation and efficiency. OT environments—once isolated and static—are now connected, intelligent, and increasingly targeted by sophisticated adversaries. This session will explore how security leaders are evolving their approach to safeguard industrial systems, supply chains, and critical operations without disrupting productivity. Discussion will focus on building resilience, improving visibility across IT/OT boundaries, and strengthening collaboration between security, engineering, and business teams to defend the enterprise from the plant floor to the cloud.